Weekly Image Challenge – March 8, 2025

A 62-year-old male presents with progressive back pain for the past 3 months. He describes the pain as dull and persistent, worse with movement but not relieved by rest.
He has also experienced fatigue, recent unintentional weight loss, and increased thirst. On examination, there is localized tenderness over the lumbar spine.
Laboratory investigations reveal: Hemoglobin: 9.8 g/dL (low), Serum calcium: 12.2 mg/dL (high) and Serum creatinine: 2.1 mg/dL (elevated).

What is the most likely diagnosis?

  1. Metastatic bone disease
  2. Multiple myeloma
  3. Osteoporosis
  4. Vertebral osteomyelitis

Answer

Coming soon!

Dr. Shayan Sirat M. Anwar | Aga Khan University Hospital, Karachi